What is GNDC?
The Gene-encoded Natural Diversity Compound Repository (GNDC) is the world's first repository that catalogs diverse natural components. It is created by using artificial intelligence and cutting-edge omics methods to annotate and gather natural components, centering on nuclear and organellar genomes of species in eight global pharmacopoeias and multi-resource data. It contains over hundreds of million natural components and has four specialized sub-databases.
The advantages of GNDC?
GNDC currently contains over hundreds of million natural components, offering expansive "chemical spaces" for drug discovery. It is not merely a data repository but also provides user-friendly tools for integrative and comparative analyses, facilitating in-depth exploration of genetic encoding mechanisms, compound diversity, and their potential pharmaceutical applications. GNDC serves as an indispensable resource of natural components and will drive the transformation of drug discovery from an "experience-driven" approach to a "big data-driven" paradigm.
The four parts of GNDC?
GNDC is organized into four specialized sub-databases: HerbalMDB for secondary metabolites, HerbalRDB for nucleic acids, HerbalPDB for peptides, and HerbalCDB for carbohydrates.