Basic Information

ID	TCMD09565
Disease	Glaucoma, Primary Open Angle
Disease related genes	SERPINA3 , ABCA1 , ABCA4 , ABO , ACTB , ACTG1 , ACTG2 , PARP1 , ADRB2 , AGER , AKT1 , ALB , ANGPT2 , ANXA5 , APBB2 , APEX1 , APOC3 , APOE , APP , AQP1 , RHOA , ARSD , AXL , BAK1 , BDNF , BMP4 , BRCA1 , C1QBP , C3 , CACNA1C , CACNA2D1 , CALCA , CAT , CAV1 , CAV2 , CD40 , CDH1 , CDH5 , CDK9 , CDKN1A , CDKN2A , CDKN2B , CDX2 , CLCN2 , CLU , CNTF , COL1A1 , COL5A1 , COL5A2 , COL8A1 , COL8A2 , COL11A1 , COL15A1 , MAP3K8 , CRYAA , CRYAB , CST3 , CCN2 , CTSD , CUX1 , CYP1A1 , CYP1B1 , CYP2C19 , CYP2D6 , CYP27A1 , DBN1 , DCN , ACE , DDIT3 , DDX3X , COCH , DLG2 , DNASE1L3 , EBF1 , EDN1 , EDNRA , EIF2D , EGFR , EGR1 , ELN , ESR1 , ESR2 , FBLN1 , FBN1 , EFEMP1 , FOXC1 , FLNB , FN1 , FUT7 , GALC , GAS1 , GJA1 , GLB1 , GMDS , CXCR3 , GRIN2B , NR3C1 , GSTM1 , GSTM2 , GSTP1 , GSTT1 , GUCY1A1 , HAS2 , HK2 , HLA-A , HLA-DQB1 , HLA-DRB1 , HES1 , HSPA1A , HSPA1B , HSPA4 , HSPA5 , HSPB1 , HSPB2 , HSPD1 , HTC2 , ICA1 , IDH3A , IFNG , IGF2 , IGFALS , IGKC , IL1A , IL1B , IL1RN , IL2 , IL2RA , IL6 , IL7 , IL9 , IL10 , ISG20 , ITGA5 , ITGAV , ITIH4 , ITPR3 , KDR , LDLR , LHCGR , LMX1B , LOXL1 , LOXL2 , LTBP2 , LTBP3 , MBL2 , MBP , MAP3K1 , MFGE8 , MMP1 , MMP2 , MMP3 , MMP9 , MMP12 , MPO , MT1A , MT1B , MT1E , MT1F , MT1G , MT1H , MT1JP , MT1M , MT1L , MT1X , COX1 , COX2 , MTHFR , ND2 , MTNR1A , MUTYH , MYOC , NFKB1 , NFKB2 , NOS2 , NOS3 , NPPA , NPPC , NTF4 , OAS3 , OGG1 , OGN , OPA1 , SIX6 , PAH , SERPINE1 , ABCB1 , PITX2 , PKHD1 , PLA2G4A , PLG , PLXNA2 , PPID , PRKAA1 , PRNP , PSD , PTEN , PTGFR , PTGS1 , PTGS2 , PTPRJ , PEX5 , RAN , RBP1 , RHO , RNR2 , ROCK1 , ROS1 , RPN2 , ATXN2 , SRL , CCL2 , CCL4 , CCL16 , CXCL5 , SFRP1 , SRSF3 , SHBG , PMEL , SIX1 , SOAT1 , SOD1 , SOD2 , SPARC , SPOCK1 , SPP1 , SPRR2A , SULT1E1 , TAP1 , TEK , TGFB1 , TGFB2 , TGFB3 , TGFBR3 , TGM2 , THBS1 , THBS2 , TIMP1 , TIMP2 , TIMP3 , TIMP4 , TLR2 , TLR4 , TNF , TNNT1 , TP53 , TP53BP2 , CRISP2 , SCGB1A1 , UROD , VAV2 , VDR , VEGFA , VEGFC , XRCC1 , CDC7 , HYAL3 , GAS7 , USO1 , RTCA , PDE5A , B4GALT3 , ARHGEF7 , HSPB3 , SELENBP1 , DCLK1 , FHL5 , ROCK2 , GDF15 , CCL4L2 , SART3 , SLC23A2 , SLC23A1 , HDAC6 , PPIF , OPTN , CALCRL , FLOT1 , ANGPTL7 , ABCC4 , RAMP2 , VAV3 , NXF1 , FBLN5 , TXNRD2 , PRPF8 , CYP46A1 , PDIA5 , STIP1 , PRDM5 , DDX20 , PADI2 , ACOT7 , MLXIP , MMRN1 , TPX2 , ARHGEF12 , SIRT1 , SEC14L2 , OPTC , HEYL , PCOLCE2 , SND1 , IL17B , HPGDS , TBK1 , MYLIP , CARD10 , TRPM5 , RHOD , IL20 , NTM , ASCC1 , HSPA14 , MZB1 , FZR1 , IL20RB , TMCO1 , CCHCR1 , SRBD1 , CHDH , LGALS14 , RPGRIP1 , ADAMTSL3 , ATP10A , SLC4A10 , BIRC6 , SEMA6A , ZP4 , ZNF410 , AFAP1 , ELOVL5 , CIAO3 , FNDC3B , FASTKD1 , AGBL2 , COL18A1 , ADAMTS10 , ASCC2 , MINDY4 , ZNF469 , SPZ1 , PLXDC2 , CNTNAP4 , MVB12B , MARCHF9 , GLCCI1 , FBLN7 , SLCO6A1 , WDR36 , ASB10 , MPP7 , PLEKHA7 , PLB1 , CNTN4 , TMTC2 , ADAMTS17 , PRSS55 , ATOH7 , MARCHF8 , SH3PXD2B , NANOS2 , ACTBL2 , GSTK1 , CCL4L1 , MIR182 , MIR210 , POTEKP , POTEM , CDKN2B-AS1 , LGTN , MTCO2P12 , MYOCOS , H3P40
Source	MalaCards;DisGeNET

Related Chinese Medicinal Materials

ID	Chinese name	Pinyin name	Property	Flavor
TCMH0002	北刘寄奴	Bei Liu Ji Nu	Cold	Bitter
TCMH0003	炒瓜蒌子	Chao Gua Lou Zi	Cold	Sweet
TCMH0004	臭灵丹草	Chou Ling Dan Cao	Cold	Pungent, bitter
TCMH0005	川射干	Chuan Ye Gan	Cold	Bitter
TCMH0006	大蓟炭	Da Ji Tan	Cool	Sweet, bitter

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Related Ingredients

ID	Ingredient name	Formula	P_value
TCMI16872	Andrographatoside	C26H42O9	9.0427542531e-45
TCMI18719	Cadaverine	C5H14N2	7.0369343686e-40
TCMI31736	polygonin	C27H44O4	4.6580226124e-35
TCMI06239	Estradiol	C18H24O2	5.4731371715e-35
TCMI02720	(E)-2,6,10-Trimethylundeca-5,9-dienol	C14H26O	1.1018436753e-34

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