Basic Information

ID	TCMD19461
Disease	Primary Myelofibrosis
Disease related genes	ABL1 , ACTB , ADCY1 , AKT1 , ALB , ALPI , ALPP , AMCN , APBB2 , XIAP , STS , BAG1 , BAK1 , BAX , BCL2 , BCL2L2 , BCR , BDNF , BID , BLVRA , BLVRB , BMP1 , BMP6 , BMP7 , BNIP3 , BRCA2 , CA2 , SLC25A20 , CALB2 , CALR , CAT , RUNX1 , CBL , CD9 , CD14 , CD34 , CD47 , CD63 , CDKN2A , CDKN2B , CEACAM5 , CHI3L1 , CHIT1 , CRP , CSF1R , CSF3 , CSF3R , CCN2 , CTNNB1 , CUX1 , ACE , DNMT1 , DNMT3A , ATN1 , EDA , ELN , ENG , EPO , EPOR , ETV6 , EZH2 , FCGR2A , FGF2 , FGF3 , FGFR1 , FKBP4 , FKBP5 , FLT1 , FLT3 , FN1 , MTOR , FZD2 , G6PD , GABPA , GATA1 , GLI1 , GLS , NR3C1 , HIF1A , HMGA1 , HP , HPGD , HSPB1 , HSPB2 , IAPP , IDH1 , IDH2 , IFI27 , IFNA1 , IFNA2 , IFNA13 , IFNG , IGF2 , CCN1 , IL1A , IL1B , IL1RN , IL2RA , IL3 , IL6 , CXCL8 , CXCR1 , CXCR2 , IRAK1 , ITGA9 , ITGB2 , JAK1 , JAK2 , JARID2 , JUN , KIT , KRT7 , LDHA , LDHB , LEP , LEPR , LGALS1 , LGALS3 , LIG3 , LIG4 , LOX , MCAM , MMP8 , MMP13 , MMP14 , MPL , MVD , MYB , MYC , GADD45B , CEACAM6 , NFE2 , NFE2L2 , NOS2 , NOS3 , NPM1 , NRAS , NR4A2 , TNFRSF11B , PAEP , PDGFB , PDGFRA , PDGFRB , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PLK1 , PPARG , PRB1 , PRG2 , MAPK1 , MAPK3 , MAPK8 , PTH , PTHLH , PTK2 , RARB , RARS1 , RET , RPS14 , S100A8 , S100A9 , S100A12 , SCT , CXCL12 , SELP , SRSF2 , SLCO2A1 , SNRPF , SOAT1 , SOD2 , SPARC , SPP1 , SRC , STAT1 , STAT3 , STAT5A , STAT5B , AURKA , TAC1 , TBXAS1 , PRDX2 , TGFB1 , TGFBR1 , TGFBR2 , THBD , THBS1 , THBS2 , THPO , THRB , THY1 , TLR4 , TNF , TNFRSF1B , TP53 , TPO , CRISP2 , TRPC4 , TYK2 , TYROBP , U2AF1 , VDR , VEGFA , WNT1 , WT1 , ZMYM2 , CXCR4 , SHOC2 , HMGA2 , GFI1B , CNTNAP1 , ENC1 , BECN1 , CD164 , DLK1 , IL18R1 , PROM1 , HSPB3 , SOCS3 , MYOM2 , NOG , SOCS6 , NCOR2 , HDAC9 , BCLAF1 , ABI1 , HDAC6 , SH2B3 , HMGXB4 , EBI3 , GDF11 , STUB1 , MRPL28 , SUB1 , FGFR1OP , NRM , VPS45 , MMRN1 , HMGXB3 , NBEAL2 , SF3B1 , SETBP1 , INTS1 , SGSM3 , BABAM1 , NXT1 , PYCARD , TBK1 , LEF1 , BCO1 , FXYD5 , TET2 , ASPN , BCOR , AGGF1 , BDP1 , BAIAP2L1 , CD177 , KIDINS220 , INTS2 , STIM2 , CIP2A , INTS3 , DERL1 , BORA , HDAC11 , MPIG6B , FIP1L1 , PRSS27 , MAGT1 , SPZ1 , BMF , ADHFE1 , APOOL , FREM1 , ZFPM1 , ASXL1 , PAOX , PRSS55 , BEND7 , BEST4 , ZBTB8OS , AGBL3 , BEND4 , MIR143 , MIR155 , MIR34A , MIR146B , BCL2L2-PABPN1 , RN7SL263P , H3P10
Source	CTD;DisGeNET

Related Chinese Medicinal Materials

ID	Chinese name	Pinyin name	Property	Flavor
TCMH0002	北刘寄奴	Bei Liu Ji Nu	Cold	Bitter
TCMH0003	炒瓜蒌子	Chao Gua Lou Zi	Cold	Sweet
TCMH0004	臭灵丹草	Chou Ling Dan Cao	Cold	Pungent, bitter
TCMH0005	川射干	Chuan Ye Gan	Cold	Bitter
TCMH0007	当药	Dang Yao	Cold	Bitter

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Related Ingredients

ID	Ingredient name	Formula	P_value
TCMI34178	Streptomycin	C21H39N7O12	2.1204827063e-64
TCMI24440	Glutamine	C5H10N2O3	2.4579544948e-43
TCMI16872	Andrographatoside	C26H42O9	1.6758939174e-37
TCMI21970	Diethylstilbestrol	C18H20O2	1.3477227867e-34
TCMI11061	Jaceosidin	C17H14O7	3.0800013108e-34

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